247069-27-8
- Product Name：2,6-Diamino-3,5-difluoropyridine
- Molecular Formula：C5H5F2N3
- Purity：99%
- Molecular Weight：145.112
Product Details
Good factory exports good 2,6-Diamino-3,5-difluoropyridine 247069-27-8
- Molecular Formula:C5H5F2N3
- Molecular Weight:145.112
- Vapor Pressure:0.056mmHg at 25°C
- Melting Point:160 °C
- Refractive Index:1.602
- Boiling Point:233.265 °C at 760 mmHg
- PKA:1.93±0.10(Predicted)
- Flash Point:94.876 °C
- PSA：64.93000
- Density:1.517 g/cm3
- LogP:1.68660
3,5-Difluoropyridine-2,6-diamine(Cas 247069-27-8) Usage
|
Physical properties |
3,5-Difluoropyridine-2,6-diamine is soluble in water (slightly). |
InChI:InChI=1/C5H5F2N3/c6-2-1-3(7)5(9)10-4(2)8/h1H,(H4,8,9,10)
247069-27-8 Relevant articles
Direct di- and triamination of polyfluoropyridines in anhydrous ammonia
Kusov, Soltan Z.,Rodionov, Vladimir I.,Vaganova, Tamara A.,Shundrina, Inna K.,Malykhin, Evgenij V.
, p. 461 - 465 (2009)
Aminodefluorination of polyfluoropyridin...
Preparation method of 3,5-difluoro-2,6-diaminopyridine
-
Paragraph 0017-0019, (2019/02/04)
The invention discloses a preparation me...
Method for preparing 2,6-diamino-3,5-difluoropyridine
-
, (2019/10/01)
The invention discloses a method for pre...
Selective mono-and diamination of polyfluorinated benzenes and pyridines with liquid ammonia
Vaganova,Kusov,Rodionov,Shundrina,Malykhin
, p. 2239 - 2246 (2008/09/20)
Amination of pentafluoropyridine, 2,3,5,...
247069-27-8 Process route
-
-
2875-18-5
2,3,5,6-tetrafluoropyridine
-
-
247069-27-8
2,6-diamino-3,5-difluoropyridine
| Conditions | Yield |
|---|---|
|
With
ammonium hydroxide;
In
ethanol;
at 30 ℃;
for 3h;
Time;
Green chemistry;
|
91% |
|
With
ammonia;
at 150 ℃;
for 67h;
Autoclave;
|
70% |
|
Multi-step reaction with 2 steps
1: 1-methyl-pyrrolidin-2-one; potassium carbonate / 40 - 100 °C
2: hydrogenchloride / water / 2 h / 20 °C
With
1-methyl-pyrrolidin-2-one; hydrogenchloride; potassium carbonate;
In
water;
|
-
-
C13H21F2N3O4S2
-
-
247069-27-8
2,6-diamino-3,5-difluoropyridine
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
water;
at 20 ℃;
for 2h;
|
95% |
247069-27-8 Upstream products
-
247069-28-9
N2,N6-dibenzyl-2,6-diamino-3,5-difluoropyridine
-
2875-18-5
2,3,5,6-tetrafluoropyridine
-
2176-62-7
2,3,4,5,6-pentachloropyridine
247069-27-8 Downstream products
-
875712-88-2
(E)-1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-isobutyryloxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
-
875712-88-2
(Z)-1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-isobutyryloxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
-
442526-91-2
1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-isobutyryloxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester
-
875712-88-2
1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-isobutyryloxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Relevant Products
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5-Chloro-2-fluoropyridineCAS：1480-65-5
-
2,4-DiaminotolueneCAS：95-80-7
-
2-Amino-3,5-difluoropyridineCAS：732306-31-9