95-80-7
- Product Name:2,4-Diaminotoluene
- Molecular Formula:C7H10N2
- Purity:99%
- Molecular Weight:122.17
Product Details
Cost-effective and customizable 2,4-Diaminotoluene 95-80-7 factory
- Molecular Formula:C7H10N2
- Molecular Weight:122.17
- Appearance/Colour:brown crystalline powder, crystals or flakes
- Vapor Pressure:0.00188mmHg at 25°C
- Melting Point:97-99 °C(lit.)
- Refractive Index:1.5103 (estimate)
- Boiling Point:292 °C at 760 mmHg
- PKA:5.02±0.10(Predicted)
- Flash Point:149.5 °C
- PSA:52.04000
- Density:1.107 g/cm3
- LogP:2.32180
2,4-Diaminotoluene(Cas 95-80-7) Usage
|
Preparation |
2,4-Diaminotoluene is prepared by hydrogenation of 2,4-dinitrotoluene using a nickel catalyst. Commercial samples often contain up to 20% of the 2,6-isomer. |
|
Air & Water Reactions |
Soluble in water, alcohol and ether. |
|
Reactivity Profile |
2,4-Diaminotoluene neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. Reacts vigorously with oxidizing agents [USCG, 1999]. |
|
Health Hazard |
2,4-Toluenediamine is a cancer-causing compound. Animal studies indicate sufficient evidence of its carcinogenicity. Oral applicationof this amine resulted in blood and liver cancers in rats and mice.The acute oral toxicity was moderate tohigh in test animals. It produced methe moglobinemia, cyanosis, and anemia. Theoral LD50 value in rats is 250–300 mg/kg.It is a mild skin irritant. The irritation effecton rabbits'eyes was moderate.Acute (short-term) exposure to high levels of toluene-2,4-diamine in humans has caused severe skin and eye irritation sometimes leading to permanent blindness. Other effects include respiratory problems, stomach gas, rise in blood pressure, dizziness, convulsions, fainting, and coma. |
|
Fire Hazard |
Noncombustible solid. It ignites when mixed with red fuming nitric acid. Reactions with strong oxidizers and hypochlorites can be violent. |
|
Flammability and Explosibility |
Nonflammable |
|
Safety Profile |
Confirmed carcinogen with experimental carcinogenic data. Poison by intraperitoneal and subcutaneous routes. Experimental reproductive effects. Human mutation data reported. A skin and eye irritant. This material has a marked toxic action upon the liver and can cause fatty degeneration of that organ. When heated to decomposition it emits toxic fumes of NOx. See also other toluenediamine entries and AROMATIC AMINES. |
|
Potential Exposure |
2,4-Diaminotoluene can be found in flexible and rigid polyurethane foams, upholstery, polyurethane coatings, for dyes used on textiles, leather, furs, in hair-dye formulations, sealants, adhesives gums and fibers. The substance is also commonly used when manufacturing other substances. |
|
Carcinogenicity |
2,4-Diaminotoluene is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. |
|
Shipping |
UN1709 2,4-Toluylenediamine, solid or 2,4Toluenediamine, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3814 2,4-Toluylenediamine, solution or 2,4-Toluenediamine, solution, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. |
|
Purification Methods |
Recrystallise the diamine from water containing a very small amount of sodium dithionite (to prevent air oxidation), and dry it under vacuum. It also crystallises from *benzene. [Beilstein 13 IV 235.] |
|
Incompatibilities |
Strong acids; chloro formates, oxidizers. |
|
Definition |
ChEBI: 2,4-diaminotoluene is an aminotoluene that is para-toluidine with an additional amino group at position 2. It has a role as a metabolite. It derives from a p-toluidine. |
|
General Description |
A colorless crystalline solid. Toxic by ingestion and inhalation. Irritates skin and eyes. Slightly soluble in water and neutrally buoyant in water. Decomposes with emission of toxic oxides of nitrogen at high temperatures. Used in making dyes. |
InChI:InChI=1/C7H10N2.ClH/c1-5-2-3-6(8)4-7(5)9;/h2-4H,8-9H2,1H3;1H
95-80-7 Relevant articles
Preparation and catalytic performance of active metal sintered membrane reactor anchored with Pt atoms
Ren, Xiaoliang,Wang, Shufang,Ding, Xiaoshu,Zhang, Dongsheng,Wang, Yanji
, p. 2848 - 2853 (2021/01/28)
In the chemical industry, reactors are t...
Designing of Highly Active and Sustainable Encapsulated Stabilized Palladium Nanoclusters as well as Real Exploitation for Catalytic Hydrogenation in Water
Patel, Anish,Patel, Anjali
, p. 803 - 820 (2020/08/12)
Abstract: Encapsulated nanoclusters base...
Fabrication of palladium nanocatalyst supported on magnetic eggshell and its catalytic character in the catalytic reduction of nitroarenes in water
?al??kan, Melike,Akay, Sema,Baran, Talat,Kayan, Berkant
, (2021/07/21)
Aromatic nitro compounds, which have goo...
Depolymerization of Technical-Grade Polyamide 66 and Polyurethane Materials through Hydrogenation
Zhou, Wei,Neumann, Paul,Al Batal, Mona,Rominger, Frank,Hashmi, A. Stephen K.,Schaub, Thomas
, p. 4176 - 4180 (2020/11/30)
Chemical recycling provides a promising ...
95-80-7 Process route
-
-
121-14-2
2,4-dinitrotoluene
-
-
618-85-9
3,5-dinitrotoluene
-
-
606-20-2
2,6-dinitrotoluene
-
-
602-01-7
1-methyl-2,3-dinitrobenzene
-
-
610-39-9
3,4-Dinitrotoluene
-
-
619-15-8
2,5-dinitrotoluene
-
-
108-71-4
3,5-diaminotoluene
-
-
823-40-5
2,6-toluenediamine
-
-
95-80-7,71111-07-4
4-methylbenzene-1,3-diamine
-
-
496-72-0
4-methyl-1,2-diaminobenzene
-
-
95-70-5
2-methyl-p-phenylenediamine
-
-
2687-25-4
3-methyl-1,2-benzenediamine
| Conditions | Yield |
|---|---|
|
With
hydrogen;
nickel;
at 120 - 140 ℃;
under 11251.1 - 22502.3 Torr;
Product distribution / selectivity;
|
-
-
102276-79-9
4,4'-dimethyl-2,3'-dinitro-ONN-azoxybenzene
-
-
95-80-7,71111-07-4
4-methylbenzene-1,3-diamine
-
-
496-72-0
4-methyl-1,2-diaminobenzene
-
-
C14H16N4O
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride; acetic acid; tin(ll) chloride;
for 3h;
Title compound not separated from byproducts;
|
95-80-7 Upstream products
-
528-75-6
2,4-dinitrobenzaldehyde
-
121-14-2
2,4-dinitrotoluene
-
610-57-1
2,4-dinitrobenzyl chloride
-
1016810-12-0
N-(3-amino-4-methyl-phenyl)-phthalimide
95-80-7 Downstream products
-
13733-32-9
N,N'-(4-methyl-m-phenylene)-bis-acetoacetamide
-
58336-28-0
7-amino-4,6-dimethyl-quinolin-2-ol
-
134668-04-5
N,N'-difurfurylidene-4-methyl-m-phenylenediamine
-
6375-16-2
2-amino-4-acetylaminotoluene
Relevant Products
-
3-hydroxy-1-methylpiperidine
CAS:3554-74-3
-
2,4,6-triamino-3,5-difluoropyridine
CAS:1190226-04-0
-
2,6-Diamino-3,5-difluoropyridine
CAS:247069-27-8
