658066-44-5
- Product Name:2-(3-chloro-5-(trifluoroMethyl)pyridin-2-yl)ethanaMine
- Molecular Formula:
- Purity:99%
- Molecular Weight:224.613
Product Details
Buy high quality and low price 2-(3-chloro-5-(trifluoroMethyl)pyridin-2-yl)ethanaMine 658066-44-5 now
- Molecular Formula:C8H8ClF3N2
- Molecular Weight:224.613
- Boiling Point:230.5±35.0 °C(Predicted)
- PKA:8.20±0.10(Predicted)
- Density:1.364±0.06 g/cm3(Predicted)
658066-44-5 Relevant articles
Design, synthesis biological activity, and docking of novel fluopyram derivatives containing guanidine group
Liang, Peibo,Shen, Shengqiang,Xu, Qingbo,Wang, Simin,Jin, Shuhui,Lu, Huizhe,Dong, Yanhong,Zhang, Jianjun
, (2020/11/17)
Succinate dehydrogenase (SDH), a crucial...
Synthesis method of benzamide compound (by machine translation)
-
Paragraph 0048; 0051; 0052; 0056; 0058; 0060; 0062; 0064, (2020/05/05)
The synthesis method of N - [2 - [3 -(tr...
CATALYTIC HYDROGENATION OF NITRILES
-
Page/Page column 14, (2018/07/22)
The present invention relates to a novel...
CATALYTIC HYDROGENATION OF NITRILES
-
Page/Page column 52-54, (2015/06/03)
The present invention relates to a novel...
658066-44-5 Process route
-
-
157764-10-8
2‐[3‐chloro‐5‐(trifluoromethyl)pyridin‐2‐yl]acetonitrile
-
-
658066-44-5
2-[3-chloro-5-(trifluoromethyl)-2-pyridyl]-1-ethanamine
| Conditions | Yield |
|---|---|
|
With
hydrogen;
In
tert-butyl methyl ether;
at 25 ℃;
for 4h;
under 15001.5 Torr;
Autoclave;
|
76.59% |
|
With
sulfuric acid; palladium on activated charcoal; tetrabutylammomium bromide; hydrogen;
In
methanol;
at 20 ℃;
for 4h;
under 3750.38 Torr;
Autoclave;
|
70% |
|
With
hydrogen;
5%-palladium/activated carbon;
In
acetic acid;
at 20 ℃;
for 15h;
under 4500.45 Torr;
Product distribution / selectivity;
|
19% |
|
With
sulfuric acid; 10 wt% Pd(OH)2 on carbon; hydrogen; sodium bromide;
In
methanol;
at 20 ℃;
under 3750.38 Torr;
Reagent/catalyst;
|
91.34 %Chromat. |
|
With
hydrogen; acetic anhydride;
at 80 ℃;
for 4h;
Reagent/catalyst;
Temperature;
|
-
-
3-chloro-5-(trifluoromethyl)-2-ethylacetamide-pyridinyl
-
-
658066-44-5
2-[3-chloro-5-(trifluoromethyl)-2-pyridyl]-1-ethanamine
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
water;
for 5h;
Product distribution / selectivity;
Heating / reflux;
|
92% |
658066-44-5 Upstream products
-
157764-10-8
2‐[3‐chloro‐5‐(trifluoromethyl)pyridin‐2‐yl]acetonitrile
-
172527-71-8
diethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)malonate
-
69045-84-7
2,3-dichloro-5-trifluoromethylpyridine
-
923251-81-4
ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-cyanoacetate
658066-44-5 Downstream products
-
658066-35-4
fluopyram
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