76469-41-5
- Product Name：2,3,5-Trifluoropyridine
- Molecular Formula：C5H2F3N
- Purity：99%
- Molecular Weight：133.073
Product Details
Good factory exports good 2,3,5-Trifluoropyridine 76469-41-5
- Molecular Formula:C5H2F3N
- Molecular Weight:133.073
- Appearance/Colour:Colorless liquid
- Refractive Index:1.422
- Boiling Point:96.7 °C at 760 mmHg
- PKA:-5.28±0.20(Predicted)
- Flash Point:12.3 °C
- PSA：12.89000
- Density:1.396 g/cm3
- LogP:1.49890
76469-41-5 Relevant articles
Mechanistic study of Ru-NHC-catalyzed hydrodefluorination of fluoropyridines: The influence of the NHC on the regioselectivity of C-F activation and chemoselectivity of C-F versus C-H bond cleavage
McKay, David,Riddlestone, Ian M.,Macgregor, Stuart A.,Mahon, Mary F.,Whittlesey, Michael K.
, p. 776 - 787 (2015/03/04)
We describe a combined experimental and ...
Catalytic hydrodefluorination of fluoroaromatics with silanes as hydrogen source at a binuclear rhodium complex: Characterization of key intermediates
Zámostná, Lada,Ahrens, Mike,Braun, Thomas
, p. 132 - 142 (2013/10/01)
Stoichiometric and catalytic hydrodefluo...
The ionic liquid [bmim]Br as an alternative medium for the catalytic cleavage of aromatic C-F and C-Cl bonds
Prikhod'ko, Sergey A.,Adonin, Nicolay Yu.,Parmon, Valentin N.
scheme or table, p. 2265 - 2268 (2010/05/18)
The potential of [bmim]Br as an alternat...
76469-41-5 Process route
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-
700-16-3
Pentafluoropyridine
-
-
82878-63-5
3,4-difluoropyridine
-
-
67815-54-7
3,4,5-trifluoropyridine
-
-
3512-16-1
2,3,4,5-tetrafluoropyridine
-
-
2875-18-5
2,3,5,6-tetrafluoropyridine
-
-
76469-41-5
2,3,5‐trifluoropyridine
| Conditions | Yield |
|---|---|
|
With
triethylsilane; α,α,α-trifluorotoluene; C64H68N2OP2Ru;
In
tetrahydrofuran;
at 69.84 ℃;
for 28h;
Time;
stereoselective reaction;
Schlenk technique;
Glovebox;
|
42 %Spectr. 22 %Spectr. 21 %Spectr. 7 %Spectr. 3 %Spectr. |
|
With
triethylsilane; α,α,α-trifluorotoluene; C64H68N2OP2Ru;
In
tetrahydrofuran;
at 89.84 ℃;
for 28h;
Time;
Temperature;
stereoselective reaction;
Schlenk technique;
Glovebox;
|
41 %Spectr. 26 %Spectr. 20 %Spectr. 8 %Spectr. 2 %Spectr. |
-
-
2875-18-5
2,3,5,6-tetrafluoropyridine
-
-
372-47-4
3-Fluoropyridine
-
-
3512-18-3
2,3,6-trifluoropyridine
-
-
76469-41-5
2,3,5‐trifluoropyridine
-
-
71902-33-5
3,5-difluoropyridine
| Conditions | Yield |
|---|---|
|
With
triethylsilane; [Rh(μ-H)(1,3-bis(diisopropylphosphanyl)propane)]2;
In
benzene-d6;
at 50 ℃;
for 48h;
regioselective reaction;
Inert atmosphere;
|
24 %Spectr. 7 %Spectr. 15 %Spectr. 8 %Spectr. |
76469-41-5 Upstream products
-
700-16-3
Pentafluoropyridine
-
2875-18-5
2,3,5,6-tetrafluoropyridine
76469-41-5 Downstream products
-
861100-90-5
7-(3,5-difluoropyridin-2-yl)-N-(4-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-amine
-
1224249-98-2
2,3,5-trifluoro-4-p-tolylpyridine
-
511522-69-3
2-chloro-3,5-difluoropyridine
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