45644-21-1

  • Product Name:6-Chloro-2-pyridinamine
  • Molecular Formula:C5H5ClN2
  • Purity:99%
  • Molecular Weight:128.561
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Product Details

Cost-effective and customizable 6-Chloro-2-pyridinamine 45644-21-1 supplier

  • Molecular Formula:C5H5ClN2
  • Molecular Weight:128.561
  • Appearance/Colour:White to light yellow powder 
  • Vapor Pressure:0.016mmHg at 25°C 
  • Melting Point:69-73 °C 
  • Refractive Index:1.607 
  • Boiling Point:255.72 °C at 760 mmHg 
  • PKA:2.76±0.24(Predicted) 
  • Flash Point:108.456 °C 
  • PSA:38.91000 
  • Density:1.326 g/cm3 
  • LogP:1.89840 

2-Amino-6-chloropyridine(Cas 45644-21-1) Usage

InChI:InChI=1/C5H5ClN2/c6-4-2-1-3-5(7)8-4/h1-3H,(H2,7,8)

45644-21-1 Relevant articles

Protein kinase inhibitor and use thereof

-

Paragraph 0091; 0102-0103, (2021/01/21)

The present invention provides a compoun...

Preparation method of 2-amino substituted six-membered nitrogen-containing heterocycle complex

-

Paragraph 0025; 0026; 0079, (2019/02/08)

The invention discloses a preparation me...

Transition-metal-free access to 2-aminopyridine derivatives from 2-fluoropyridine and acetamidine hydrochloride

Li, Yibiao,Huang, Shuo,Liao, Chunshu,Shao, Yan,Chen, Lu

supporting information, p. 7564 - 7567 (2018/11/02)

Under catalyst-free conditions, an effic...

Catalytic application of 1,3,5-triazine-pentaethylenehexamine polymer-supported palladium nanoparticles in the convenient reduction of nitroarenes with sodium borohydride or hydrazine

Gen?, Hayriye,Zengin, Mustafa,Kü?ükislamo?lu, Mustafa,Imamoglu, Mustafa,Toplan, Hüseyin ?zkan,Arslan, Mustafa

, p. 784 - 792 (2017/11/20)

The catalytic activity of 1,3,5-triazine...

45644-21-1 Process route

2-nitro-6-chloro-pyridine
94166-64-0

2-nitro-6-chloro-pyridine

6-chloropyridin-2-amine
45644-21-1

6-chloropyridin-2-amine

Conditions
Conditions Yield
With sodium tetrahydroborate; In ethanol; water; at 20 ℃; for 1.5h; under 760.051 Torr; Reagent/catalyst; Solvent;
98%
With sodium tetrahydroborate; In ethanol; water; at 20 ℃; for 4h; chemoselective reaction;
97%
2,6-dichloropyridine
2402-78-0

2,6-dichloropyridine

6-chloropyridin-2-amine
45644-21-1

6-chloropyridin-2-amine

Conditions
Conditions Yield
With ammonium hydroxide; at 125 ℃; for 5h; under 1500.12 Torr;
79%
With ammonium hydroxide; In water; at 180 ℃; for 12h;
77%
With ammonia; In water; at 150 ℃; for 6h;
70%
With ammonium hydroxide; at 180 ℃; for 40h;
32%
With ammonia; In isopropyl alcohol; at 160 ℃; for 15h; Microwave irradiation;
28%
With ammonium hydroxide; at 180 - 190 ℃;
With ammonium hydroxide; In ethanol;
With ammonia; In ethanol; at 160 - 165 ℃; for 60h;
With ammonium hydroxide; In ethanol;

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