20885-12-5
- Product Name：2-Chloro-6-fluorpyridine
- Molecular Formula：C5H3ClFN
- Purity：99%
- Molecular Weight：131.537
Product Details
Cost-effective customized wholesale 2-Chloro-6-fluorpyridine 20885-12-5
- Molecular Formula:C5H3ClFN
- Molecular Weight:131.537
- Appearance/Colour:Light yellow needles
- Vapor Pressure:2.07mmHg at 25°C
- Melting Point:31.0 to 35.0 °C
- Refractive Index:1.503
- Boiling Point:169.2 °C at 760 mmHg
- PKA:-2.45±0.10(Predicted)
- Flash Point:56.1 °C
- PSA：12.89000
- Density:1.331 g/cm3
- LogP:1.87410
2-CHLORO-6-FLUOROPYRIDINE(Cas 20885-12-5) Usage
|
Synthesis |
However, a recent study demonstrated that a range of substituted pyridines reacted with fluorine diluted with nitrogen giving 2-fluoropyridine derivatives in acceptable yields. Thus, 2-chloropyridine gave mostly 2-chloro-6-fluoropyridine. |
InChI:InChI=1/C5H3ClFN/c6-4-2-1-3-5(7)8-4/h1-3H
20885-12-5 Relevant articles
Elemental fluorine. Part 10.1 Selective fluorination of pyridine, quinoline and quinoxaline derivatives with fluorine-iodine mixtures
Chambers, Richard D.,Parsons, Mandy,Sandford, Graham,Skinner, Christopher J.,Atherton, Malcolm J.,Moilliet, John S.
, p. 803 - 810 (2007/10/03)
Selective fluorination of a range of pyr...
Preparation of 2-Fluoropyridines via Base-Induced Decomposition of N-Fluoropyridinium Salts
Umemoto, Teruo,Tomizawa, Ginjiro
, p. 1726 - 1731 (2007/10/02)
N-Fluoropyridinium salts with either BF4...
DIRECT FLUORINATION OF SUBSTITUTED PYRIDINES
Puy, Michael Van Der
, p. 255 - 258 (2007/10/02)
The direct fluorination of pyridines bea...
20885-12-5 Process route
-
-
119071-51-1
C5H4ClFN(1+)*BF4(1-)
-
-
109-09-1
2-chloropyridine
-
-
2402-78-0
2,6-dichloropyridine
-
-
1513-65-1
2,6-difluoro pyridine
-
-
20885-12-5
2-chloro-6-fluoropyridine
| Conditions | Yield |
|---|---|
|
With
triethylamine;
for 0.0833333h;
Ambient temperature;
|
1 % Chromat. 2.5 % Chromat. 3 % Chromat. 72 % Chromat. |
-
-
109-09-1
2-chloropyridine
-
-
2402-78-0
2,6-dichloropyridine
-
-
1513-65-1
2,6-difluoro pyridine
-
-
20885-12-5
2-chloro-6-fluoropyridine
| Conditions | Yield |
|---|---|
|
With
fluorine;
at 0 ℃;
|
20885-12-5 Upstream products
-
109-09-1
2-chloropyridine
-
119071-51-1
C5H4ClFN(1+)*BF4(1-)
20885-12-5 Downstream products
-
1095223-59-8
1-(6-chloro-2-fluoro-pyridin-3-yl)-2-(3,4-dichloro-phenoxy)-ethanone
-
1095223-57-6
1-(6-chloro-2-fluoro-pyridin-3-yl)-2-(4-chloro-phenoxy)-ethanone
-
1095223-55-4
1-(6-chloro-2-fluoro-pyridin-3-yl)-2-phenoxy-ethanone
-
1095223-51-0
2-benzyloxy-1-(6-chloro-2-fluoro-pyridin-3-yl)-ethanone
Relevant Products
-
5-Chloro-2-fluoropyridineCAS：1480-65-5
-
2-AminopyridineCAS：504-29-0
-
6-Fluoronicotinic acidCAS：403-45-2